Human milk oligosaccharides survive intestinal transit

Human milk oligosaccharides: the novel modulator of intestinal microbiota.

Human milk, which nourishes the early infants, is a source of bioactive components for the infant growth, development and commensal formulation as well. Human milk oligosaccharide is a group of complex and diverse glycans that is apparently not absorbed in human gastrointestinal tract. Although most mammalian milk contains oligosaccharides, oligosaccharides in human milk exhibit unique features...

Oligosaccharides of Human Milk

Two new octasaccharides were isolated from human milk of a nonsecretor Lewis a+bindividual. Structural studies by sequential enzymic degradation and by quantitative methylation analysis revealed that their structures were as follows: Gal/31 + 3 (Fuccul + 4) GlcNAcPl + 3Gal/H -+ 4 (Fucal -+ 3) GlcNAcPl + 3Gal/31+ 4Glc, Gal/?1 + 4 (Fuccul -+ 3) GlcNAcj31 + 3Gal/31 -+ 4 (Fuccul -+ 3) GlcNAcj31 + 3...

5410 Oligosaccharides of Human Milk

Two new octasaccharides were isolated from human milk of a nonsecretor Lewis a+bindividual. Structural studies by sequential enzymic degradation and by quantitative methylation analysis revealed that their structures were as follows: Gal/31 + 3 (Fuccul + 4) GlcNAcPl + 3Gal/H -+ 4 (Fucal -+ 3) GlcNAcPl + 3Gal/31+ 4Glc, Gal/?1 + 4 (Fuccul -+ 3) GlcNAcj31 + 3Gal/31 -+ 4 (Fuccul -+ 3) GlcNAcj31 + 3...

Regulatory Aspects of Human Milk Oligosaccharides.

Human milk oligosaccharides are key components of human milk and appear in various compositions and concentrations in all human milks. In regulatory sense human milk oligosaccharides are classified as novel foods or novel food ingredients requiring safety assessment. In addition, if any health messages are intended to be used also health claim regulations apply. This chapter reviews the regulat...

Human Milk Oligosaccharides Important for Infant Defense